Spyre Therapeutics Stock Target Price and Analyst Consensus

SYRE Stock   33.56  0.40  1.18%   
The current analyst and expert consensus on Spyre Therapeutics is Strong Buy, with 10 strong buy opinions. The current projected Spyre Therapeutics target price consensus is 56.71 with 11 analyst opinions. Check out Macroaxis Advice on Spyre Therapeutics to cross-verify analyst projections. Unlike analyst recommendations, Macroaxis provides advice only from the perspective of investor risk tolerance and investment horizon.
For information on how to trade Spyre Stock refer to our How to Trade Spyre Stock guide.
The most common way Spyre Therapeutics analysts use to provide recommendation to the public is financial statements analysis. Many experts also interview Spyre Therapeutics executives and customers to further validate their buy or sell advice. Spyre Therapeutics buy-or-sell recommendation module provides average expert sentiment on the projected Spyre Therapeutics target price to derive its highest and lowest estimates based on projected price volatility of 3.7307.
Lowest Forecast
51.61
Highest Forecast
62.95
Target Price
56.71
As of February 11, 2026, Gross Profit is expected to decline to about 757.5 K. The current year's Pretax Profit Margin is expected to grow to -417.78. At present, Spyre Therapeutics' Other Current Liabilities is projected to increase significantly based on the last few years of reporting. The current year's Total Current Liabilities is expected to grow to about 65.3 M, whereas Retained Earnings are projected to grow to (831.4 M).
It's important to approach Spyre Therapeutics' target price projections with caution. While they can be useful as part of a broader investment strategy, they are inherently speculative and subject to various kinds of risk, including market volatility and unforeseen external factors. Always consider multiple aspects and do your own research when making investment decisions.

Spyre Therapeutics Target Price Consensus

Spyre target price is determined by taking all analyst projections and averaging them out. There is no one specific way to measure analysts' performance other than comparing it to past results via a very sophisticated attribution analysis. Spyre Therapeutics' target price projections below should be used in combination with other traditional price prediction techniques such as stock price forecasting, investor sentiment analysis, technical analysis, earnings estimate, and various momentum models.
   11  Strong Buy
Most Spyre analysts issue ratings four times a year, at intervals of three months. Ratings are usually accompanied by a target price to help potential investors understand Spyre stock's fair price compared to its market value. Analysts arrive at stock ratings after researching the public financial statements of Spyre Therapeutics, talking to its executives and customers, or listening to those companies' conference calls.
Macroaxis Advice   Exposure   Valuation

Spyre Therapeutics Target Price Projection

Spyre Therapeutics' current and average target prices are 33.56 and 56.71, respectively. The current price of Spyre Therapeutics is the price at which Spyre Therapeutics is currently trading. On the other hand, Spyre Therapeutics' target price is what analysts think the stock is worth. The more significant the discrepancy between the two prices, the more it stimulates investors to act.

Current Price

Spyre Therapeutics Market Quote on 11th of February 2026

Low Price33.19Odds
High Price34.93Odds

33.56

Target Price

Analyst Consensus On Spyre Therapeutics Target Price

Low Estimate51.61Odds
High Estimate62.95Odds

56.7143

Historical Lowest Forecast  51.61 Target Price  56.71 Highest Forecast  62.95
Note that most analysts generally publish their price targets in research reports on specific companies, along with recommendations for the company's stock.Although price targets are often quoted in the financial news media, there could be a delay between the publication of the latest analyst outlook on Spyre Therapeutics and the information provided on this page.

Spyre Therapeutics Analyst Ratings

Spyre Therapeutics' analyst stock recommendations are determined by taking an average estimate of all analysts we track and classifying them as Strong Buy, Buy, Hold, Strong Sell, or Sell. Ratings generally communicate what analysts sense about Spyre Therapeutics stock, and they use a lot of effort and time to analyze it and arrive at a rating. That suggests that analyst recommendations are the outcome of an objective and thorough examination of Spyre Therapeutics' financials, market performance, and future outlook by experienced professionals. Spyre Therapeutics' historical ratings below, therefore, can serve as a valuable tool for investors.

Analyst Consensus Breakdown

Average Consensus Estimates

Analysts determine stock price targets through various methods, including financial modeling, peer comparison, and company analysis. The stock price target is the analyst's best estimate of the future price of a stock and is used by investors to make investment decisions. However, it is important to note that stock price targets are not guaranteed, and the actual price of a stock can differ significantly from the target due to various factors such as market conditions, economic events, and company developments.

Steps to utilize Spyre Therapeutics price targets

Spyre Therapeutics' stock target price is an estimate of its future price, usually made by analysts. Using Spyre Therapeutics' target price to determine if it is a suitable investment can be done through the following steps:
  • Look at Spyre Therapeutics' target prices provided by various analysts and compare them. This can help you gain a more balanced view of the Stock's potential.
  • Look at the analyst's track record to determine if they have a history of accurately predicting stock prices.
  • Look at the Company's financials, including revenue, earnings, and debt, to determine if it is in good financial health.
  • Consider market conditions. For example, take into account the state of the economy, competition, and regulatory environment, to determine if Spyre Therapeutics' stock is likely to perform well.
  • Diversify your portfolio and do not rely solely on stock target prices to make investment decisions. Invest in a mix of stocks, bonds, and other assets to manage risk.
Remember that stock target prices are just estimates and are subject to change. Therefore, using them as one factor in a larger investment strategy is essential rather than relying solely on them to make decisions.

Additional Spyre Therapeutics Value Projection Modules

Most investment researchers agree that the mispricing and readjustment of any Stock value happens often and is sometimes even predictable, but there is no strong theory explaining why it happens. The current price of Spyre Therapeutics is a key component of Spyre Therapeutics valuation and have some predictive power on the future returns of a Spyre Therapeutics.
Hype
Prediction
LowEstimatedHigh
29.9433.6737.40
Details
Intrinsic
Valuation
LowRealHigh
30.2040.0243.75
Details
Earnings
Estimates (0)
LowProjected EPSHigh
-1.14-0.7-0.19
Details

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When determining whether Spyre Therapeutics is a strong investment it is important to analyze Spyre Therapeutics' competitive position within its industry, examining market share, product or service uniqueness, and competitive advantages. Beyond financials and market position, potential investors should also consider broader economic conditions, industry trends, and any regulatory or geopolitical factors that may impact Spyre Therapeutics' future performance. For an informed investment choice regarding Spyre Stock, refer to the following important reports:
Check out Macroaxis Advice on Spyre Therapeutics to cross-verify analyst projections. Unlike analyst recommendations, Macroaxis provides advice only from the perspective of investor risk tolerance and investment horizon.
For information on how to trade Spyre Stock refer to our How to Trade Spyre Stock guide.
You can also try the Latest Portfolios module to quick portfolio dashboard that showcases your latest portfolios.
Please note, the presentation of Spyre Therapeutics' financial position, as portrayed in its financial statements, is often influenced by management's estimates, judgments, and sometimes even manipulations. In the best case, Spyre Therapeutics' management is honest, while the outside auditors are strict and uncompromising. Please utilize our Beneish M Score to check the likelihood of Spyre Therapeutics' management manipulating its earnings.