Spero Therapeutics Price To Earning vs. Net Income

SPRO Stock  USD 2.30  0.10  4.17%   
Based on Spero Therapeutics' profitability indicators, Spero Therapeutics may not be well positioned to generate adequate gross income at this time. It has a very high odds of underperforming in March. Profitability indicators assess Spero Therapeutics' ability to earn profits and add value for shareholders. As of the 21st of February 2026, Price To Sales Ratio is likely to drop to 1.27. In addition to that, Days Sales Outstanding is likely to drop to 288.64. At this time, Spero Therapeutics' Income Quality is very stable compared to the past year. As of the 21st of February 2026, Gross Profit is likely to grow to about (53.3 M). In addition to that, Pretax Profit Margin is likely to drop to -1.35
For Spero Therapeutics profitability analysis, we use financial ratios and fundamental drivers that measure the ability of Spero Therapeutics to generate income relative to revenue, assets, operating costs, and current equity. These fundamental indicators attest to how well Spero Therapeutics utilizes its assets to generate profit and value for its shareholders. The profitability module also shows relationships between Spero Therapeutics's most relevant fundamental drivers. It provides multiple suggestions of what could affect the performance of Spero Therapeutics over time as well as its relative position and ranking within its peers.

Spero Therapeutics' Revenue Breakdown by Earning Segment

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To learn how to invest in Spero Stock, please use our How to Invest in Spero Therapeutics guide.The next projected EPS of Spero Therapeutics is estimated to be -0.025 with future projections ranging from a low of -0.025 to a high of -0.025. Spero Therapeutics' most recent 12-month trailing earnings per share (EPS TTM) is at -0.79. Please be aware that the consensus of earnings estimates for Spero Therapeutics is based on EPS before non-recurring items and includes expenses related to employee stock options.
 
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Spero Therapeutics is projected to generate -0.025 in earnings per share on the 31st of December 2025. Spero Therapeutics earnings estimates show analyst consensus about projected Spero Therapeutics EPS (Earning Per Share). It derives the highest and the lowest estimates based on Spero Therapeutics' historical volatility. Many public companies, such as Spero Therapeutics, manage the perception of their earnings on a regular basis to make sure that analyst estimates are accurate. Future earnings calculations are also an essential input when attempting to value a firm.

Spero Therapeutics Revenue Breakdown by Earning Segment

By analyzing Spero Therapeutics' earnings estimates, investors can diagnose different trends across Spero Therapeutics' analyst sentiment over time as well as compare current estimates against different timeframes.
Will Biotechnology sector continue expanding? Could Spero diversify its offerings? Factors like these will boost the valuation of Spero Therapeutics. If investors know Spero will grow in the future, the company's valuation will be higher. Accurate valuation requires analyzing both current fundamentals and future growth trajectories. Every Spero Therapeutics data point contributes insight, yet successful analysis hinges on identifying the most consequential variables.
Quarterly Earnings Growth
0.753
Earnings Share
(0.79)
Revenue Per Share
0.73
Quarterly Revenue Growth
(0.60)
Return On Assets
(0.30)
Understanding Spero Therapeutics requires distinguishing between market price and book value, where the latter reflects Spero's accounting equity. The concept of intrinsic value - what Spero Therapeutics' is actually worth based on fundamentals - guides informed investors toward better entry and exit points. Seasoned market participants apply comprehensive analytical frameworks to derive fundamental worth and identify mispriced opportunities. Market sentiment, economic cycles, and investor behavior can push Spero Therapeutics' price substantially above or below its fundamental value.
Please note, there is a significant difference between Spero Therapeutics' value and its price as these two are different measures arrived at by different means. Investors typically determine if Spero Therapeutics is a good investment by looking at such factors as earnings, sales, fundamental and technical indicators, competition as well as analyst projections. In contrast, Spero Therapeutics' trading price reflects the actual exchange value where willing buyers and sellers reach mutual agreement.

Spero Therapeutics Net Income vs. Price To Earning Fundamental Analysis

Comparative valuation techniques use various fundamental indicators to help in determining Spero Therapeutics's current stock value. Our valuation model uses many indicators to compare Spero Therapeutics value to that of its competitors to determine the firm's financial worth.
Spero Therapeutics is currently regarded as top stock in price to earning category among its peers. It is rated below average in net income category among its peers . Spero Therapeutics reported last year Net Loss of (61.71 Million). The reason why the comparable model can be used in almost all circumstances is due to the vast number of multiples that can be utilized, such as the price-to-earnings (P/E), price-to-book (P/B), price-to-sales (P/S), price-to-cash flow (P/CF), and many others. The P/E ratio is the most commonly used of these ratios because it focuses on the Spero Therapeutics' earnings, one of the primary drivers of an investment's value.

Spero Net Income vs. Price To Earning

Price to Earnings ratio is typically used for current valuation of a company and is one of the most popular ratios that investors monitor daily. Holding a low PE stock is less risky because when a company's profitability falls, it is likely that earnings will also go down as well. In other words, if you start from a lower position, your downside risk is limited. There are also some investors who believe that low Price to Earnings ratio reflects the low pricing because a given company is in trouble. On the other hand, a higher PE ratio means that investors are paying more for each unit of profit.

Spero Therapeutics

P/E

 = 

Market Value Per Share

Earnings Per Share

 = 
81.20 X
Generally speaking, the Price to Earnings ratio gives investors an idea of what the market is willing to pay for the company's current earnings.
Net income is the profit of a company for the reporting period, which is derived after taking revenues and gains and subtracting all expenses and losses. Net income is one of the most-watched numbers by money managers as well as individual investors.

Spero Therapeutics

Net Income

 = 

(Rev + Gain)

-

(Exp + Loss)

 = 
(68.57 M)
Because income is reported on the Income Statement of a company and is measured in dollars some investors prefer to use Profit Margin, which measures income as a percentage of sales.

Spero Net Income Comparison

Spero Therapeutics is currently under evaluation in net income category among its peers.

Spero Therapeutics Profitability Projections

The most important aspect of a successful company is its ability to generate a profit. For investors in Spero Therapeutics, profitability is also one of the essential criteria for including it into their portfolios because, without profit, Spero Therapeutics will eventually generate negative long term returns. The profitability progress is the general direction of Spero Therapeutics' change in net profit over the period of time. It can combine multiple indicators of Spero Therapeutics, where stable trends show no significant progress. An accelerating trend is seen as positive, while a decreasing one is unfavorable. A rising trend means that profits are rising, and operational efficiency may be rising as well. A decreasing trend is a sign of poor performance and may indicate upcoming losses.
Last ReportedProjected for Next Year
Accumulated Other Comprehensive Income-2.3 K-2.4 K
Interest Income5.4 M5.7 M
Operating Income-66 M-69.3 M
Net Loss-61.7 M-64.8 M
Income Before Tax-61.7 M-64.8 M
Total Other Income Expense Net5.5 M5.8 M
Net Loss-41.8 M-43.9 M
Net Loss-61.7 M-64.8 M
Income Tax ExpenseM3.1 M
Net Interest Income5.4 M5.7 M
Non Operating Income Net Other749.7 K1.2 M
Change To Netincome18.1 M19 M
Net Loss(1.14)(1.20)
Income Quality 0.39  0.57 
Net Income Per E B T 0.81  0.66 

Spero Profitability Driver Comparison

Profitability drivers are factors that can directly affect your investment outlook on Spero Therapeutics. Investors often realize that things won't turn out the way they predict. There are maybe way too many unforeseen events and contingencies during the holding period of Spero Therapeutics position where the market behavior may be hard to predict, tax policy changes, gold or oil price hikes, calamities change, and many others. The question is, are you prepared for these unexpected events? Although some of these situations are obviously beyond your control, you can still follow the important profit indicators to know where you should focus on when things like this occur. Below are some of the Spero Therapeutics' important profitability drivers and their relationship over time.

Spero Therapeutics Earnings Estimation Breakdown

The calculation of Spero Therapeutics' earning per share is based on the data from the past 12 consecutive months, used for reporting the company's financial figures. The next projected EPS of Spero Therapeutics is estimated to be -0.025 with the future projection ranging from a low of -0.025 to a high of -0.025. Please be aware that this consensus of annual earnings estimates for Spero Therapeutics is based on EPS before non-recurring items and includes expenses related to employee stock options.
Last Reported EPS
-0.13
-0.03
Lowest
Expected EPS
-0.025
-0.03
Highest

Spero Therapeutics Earnings Projection Consensus

Suppose the current estimates of Spero Therapeutics' value are higher than the current market price of the Spero Therapeutics stock. In this case, investors may conclude that Spero Therapeutics is overpriced and will exhibit bullish sentiment. On the other hand, if the present value is lower than the stock price, analysts may conclude that the market undervalues the equity. These scenarios may suggest that the market is not as efficient as it should be at the estimation time, and Spero Therapeutics' stock will quickly adjusts to the new information provided by the consensus estimate.
Number of AnalystsHistorical AccuracyLast Reported EPSEstimated EPS for 31st of December 2025Current EPS (TTM)
116.61%
-0.13
-0.025
-0.79

Spero Therapeutics Earnings per Share Projection vs Actual

Actual Earning per Share of Spero Therapeutics refers to what the company shows during its earnings calls or quarterly reports. The Expected EPS is what analysts covering Spero Therapeutics predict the company's earnings will be in the future. The higher the earnings per share of Spero Therapeutics, the better is its profitability. While calculating the Earning per Share, we use the weighted ratio, as the number of shares outstanding can change over time.

Spero Therapeutics Estimated Months Earnings per Share

For an investor who is primarily interested in generating an income out of investing in entities such as Spero Therapeutics, the EPS ratio can tell if the company is intending to increase its current dividend. Although EPS is an essential tool for investors, it should not be used in isolation. EPS of Spero Therapeutics should always be considered in relation to other companies to make a more educated investment decision.

Spero Quarterly Analyst Estimates and Surprise Metrics

Earnings surprises can significantly impact Spero Therapeutics' stock price both in the short term and over time. Negative earnings surprises usually result in a price decline. However, it has been seen that positive earnings surprises lead to an immediate rise in a stock's price and a gradual increase over time. This is why we often hear news about some companies beating earning projections. Financial analysts spend a large amount of time predicting earnings per share (EPS) along with other important future indicators. Many analysts use forecasting models, management guidance, and additional fundamental information to derive an EPS estimate.
Reported
Fiscal Date
Estimated EPS
Reported EPS
Surprise
2025-11-17
2025-09-30-0.39-0.130.2666 
2025-08-12
2025-06-30-0.57-0.030.5494 
2025-05-13
2025-03-31-0.55-0.24720.302855 
2025-03-11
2024-12-31-0.31-0.3669-0.056918 
2024-11-11
2024-09-30-0.5-0.320.1836 
2024-08-05
2024-06-30-0.38-0.330.0513 
2024-05-15
2024-03-31-0.04-0.24-0.2500 
2024-03-13
2023-12-31-0.10.961.061060 
2023-11-13
2023-09-30-0.030.040.07233 
2023-08-10
2023-06-30-0.34-0.230.1132 
2023-05-11
2023-03-31-0.33-0.250.0824 
2023-03-30
2022-12-310.040.550.511275 
2022-11-14
2022-09-30-0.3-0.33-0.0310 
2022-08-10
2022-06-30-0.93-0.870.06
2022-05-16
2022-03-31-0.87-1.01-0.1416 
2022-03-31
2021-12-31-0.75-0.9-0.1520 
2021-11-10
2021-09-30-0.66-0.7-0.04
2021-08-05
2021-06-30-0.75-0.630.1216 
2021-05-06
2021-03-31-0.64-0.66-0.02
2021-03-11
2020-12-31-0.74-0.680.06
2020-11-05
2020-09-30-0.87-0.860.01
2020-08-06
2020-06-30-1.12-0.850.2724 
2020-05-08
2020-03-31-1.25-1.190.06
2020-03-16
2019-12-31-1.08-1.32-0.2422 
2019-11-04
2019-09-30-0.85-0.95-0.111 
2019-08-08
2019-06-30-0.65-0.74-0.0913 
2019-05-09
2019-03-31-0.78-0.290.4962 
2019-03-14
2018-12-31-0.75-0.60.1520 
2018-11-08
2018-09-30-0.63-0.60.03
2018-08-09
2018-06-30-0.77-0.690.0810 
2018-05-10
2018-03-31-1.2-0.740.4638 
2017-12-14
2017-09-30-2.43-36.02-33.591382 
2017-08-30
2017-06-300-2.96-2.96
2017-05-04
2017-03-310-0.51-0.51

Use Spero Therapeutics in pair-trading

One of the main advantages of trading using pair correlations is that every trade hedges away some risk. Because there are two separate transactions required, even if Spero Therapeutics position performs unexpectedly, the other equity can make up some of the losses. Pair trading also minimizes risk from directional movements in the market. For example, if an entire industry or sector drops because of unexpected headlines, the short position in Spero Therapeutics will appreciate offsetting losses from the drop in the long position's value.

Spero Therapeutics Pair Trading

Spero Therapeutics Pair Trading Analysis

The ability to find closely correlated positions to Spero Therapeutics could be a great tool in your tax-loss harvesting strategies, allowing investors a quick way to find a similar-enough asset to replace Spero Therapeutics when you sell it. If you don't do this, your portfolio allocation will be skewed against your target asset allocation. So, investors can't just sell and buy back Spero Therapeutics - that would be a violation of the tax code under the "wash sale" rule, and this is why you need to find a similar enough asset and use the proceeds from selling Spero Therapeutics to buy it.
The correlation of Spero Therapeutics is a statistical measure of how it moves in relation to other instruments. This measure is expressed in what is known as the correlation coefficient, which ranges between -1 and +1. A perfect positive correlation (i.e., a correlation coefficient of +1) implies that as Spero Therapeutics moves, either up or down, the other security will move in the same direction. Alternatively, perfect negative correlation means that if Spero Therapeutics moves in either direction, the perfectly negatively correlated security will move in the opposite direction. If the correlation is 0, the equities are not correlated; they are entirely random. A correlation greater than 0.8 is generally described as strong, whereas a correlation less than 0.5 is generally considered weak.
Correlation analysis and pair trading evaluation for Spero Therapeutics can also be used as hedging techniques within a particular sector or industry or even over random equities to generate a better risk-adjusted return on your portfolios.
Pair CorrelationCorrelation Matching

Use Investing Themes to Complement your Spero Therapeutics position

In addition to having Spero Therapeutics in your portfolios, you can quickly add positions using our predefined set of ideas and optimize them against your very unique investing style. A single investing idea is a collection of funds, stocks, ETFs, or cryptocurrencies that are programmatically selected from a pull of investment themes. After you determine your investment opportunity, you can then find an optimal portfolio that will maximize potential returns on the chosen idea or minimize its exposure to market volatility.

Did You Try This Idea?

Run Books Thematic Idea Now

Books
Books Theme
Companies involved in publishing of books, newspapers, periodicals and other mass publications. The Books theme has 45 constituents at this time.
You can either use a buy-and-hold strategy to lock in the entire theme or actively trade it to take advantage of the short-term price volatility of individual constituents. Macroaxis can help you discover thousands of investment opportunities in different asset classes. In addition, you can partner with us for reliable portfolio optimization as you plan to utilize Books Theme or any other thematic opportunities.
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When determining whether Spero Therapeutics offers a strong return on investment in its stock, a comprehensive analysis is essential. The process typically begins with a thorough review of Spero Therapeutics' financial statements, including income statements, balance sheets, and cash flow statements, to assess its financial health. Key financial ratios are used to gauge profitability, efficiency, and growth potential of Spero Therapeutics Stock. Outlined below are crucial reports that will aid in making a well-informed decision on Spero Therapeutics Stock:
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To learn how to invest in Spero Stock, please use our How to Invest in Spero Therapeutics guide.
You can also try the Portfolio Diagnostics module to use generated alerts and portfolio events aggregator to diagnose current holdings.
To fully project Spero Therapeutics' future profitability, investors should examine all historical financial statements. These statements provide investors with a comprehensive snapshot of the financial position of Spero Therapeutics at a specified time, usually calculated after every quarter, six months, or one year. Three primary documents fall into the category of financial statements. These documents include Spero Therapeutics' income statement, its balance sheet, and the statement of cash flows.
Potential Spero Therapeutics investors and stakeholders can use historical trends found within financial statements to determine how well the company is positioned for the future. Although Spero Therapeutics investors may work on each financial statement separately, they are all related. The changes in Spero Therapeutics's assets and liabilities, for example, are also reflected in the revenues and expenses that we see on Spero Therapeutics's income statement, which results in the company's gains or losses. Cash flows can provide more information regarding cash listed on a balance sheet but not equivalent to net income shown on the income statement. Please read more on our technical analysis and fundamental analysis pages.