Upstream Bio Stock Analysis

UPB Stock   27.07  0.08  0.29%   
At present, Upstream Bio's Short and Long Term Debt Total is projected to increase significantly based on the last few years of reporting. The current year's Short Term Debt is expected to grow to about 850.1 K, whereas Net Debt is projected to grow to (277.1 M). With a high degree of financial leverage come high-interest payments, which usually reduce Upstream Bio's Earnings Per Share (EPS).
 
Debt Ratio  
First Reported
2010-12-31
Previous Quarter
0.004378
Current Value
0.003402
Quarterly Volatility
0.00119824
 
Credit Downgrade
 
Yuan Drop
 
Covid
The current year's Liabilities And Stockholders Equity is expected to grow to about 581.7 M, whereas Total Current Liabilities is forecasted to decline to about 8.1 M.
Upstream Bio is undervalued with Real Value of 34.02 and Target Price of 49.75. The main objective of Upstream Bio stock analysis is to determine its intrinsic value, which is an estimate of what Upstream Bio is worth, separate from its market price. There are two main types of Upstream Bio's stock analysis: fundamental analysis and technical analysis.
The Upstream Bio stock is traded in the USA on NASDAQ Exchange, with the market opening at 09:30:00 and closing at 16:00:00 every Mon,Tue,Wed,Thu,Fri except for officially observed holidays in the USA. Here, you can get updates on important government artifacts, including earning estimates, SEC corporate filings, announcements, and Upstream Bio's ongoing operational relationships across important fundamental and technical indicators.
Check out World Market Map to better understand how to build diversified portfolios, which includes a position in Upstream Bio. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in main economic indicators.
For information on how to trade Upstream Stock refer to our How to Trade Upstream Stock guide.

Upstream Stock Analysis Notes

About 15.0% of the company outstanding shares are owned by insiders. The book value of Upstream Bio was at this time reported as 7.01. The company recorded a loss per share of 6.4. Upstream Bio had not issued any dividends in recent years. For more information please call MD MPH at 781 208 2466 or visit https://upstreambio.com.

Upstream Bio Quarterly Total Revenue

683,000

Upstream Bio Investment Alerts

Many investors view ongoing market volatility as an opportunity to purchase more stocks at a favorable price or short it to generate a bearish trend profit opportunity. If you are one of those investors, make sure you clearly understand the position you are entering. Upstream Bio's investment alerts are automatically generated signals that are significant enough to either complement your investing judgment regarding Upstream Bio or challenge it. These alerts can help you understand what you are buying and avoid costly mistakes.
Upstream Bio appears to be risky and price may revert if volatility continues
Upstream Bio has high likelihood to experience some financial distress in the next 2 years
The company reported the last year's revenue of 2.37 M. Reported Net Loss for the year was (62.81 M) with profit before taxes, overhead, and interest of 2.8 M.
Upstream Bio generates negative cash flow from operations
Over 93.0% of the company outstanding shares are owned by institutional investors
Latest headline from news.google.com: Upstream Bio Shares Down 3.4 percent - Time to Sell - MarketBeat

Upstream Largest EPS Surprises

Earnings surprises can significantly impact Upstream Bio's stock price both in the short term and over time. Negative earnings surprises usually result in a price decline. However, it has been seen that positive earnings surprises lead to an immediate rise in a stock's price and a gradual increase over time. This is why we often hear news about some companies beating earning projections. Financial analysts spend a large amount of time predicting earnings per share (EPS) along with other important future indicators. Many analysts use forecasting models, management guidance, and additional fundamental information to derive an EPS estimate.
Reported
Fiscal Date
Estimated EPS
Reported EPS
Surprise
2025-08-06
2025-06-30-0.61-0.74-0.1321 
2025-03-12
2024-12-31-0.5403-0.410.130324 
2025-11-05
2025-09-30-0.77-0.630.1418 
View All Earnings Estimates

Upstream Bio Environmental, Social, and Governance (ESG) Scores

Upstream Bio's ESG score is a quantitative measure that evaluates Upstream Bio's performance and commitment regarding environmental, social, and governance (ESG) factors. These scores are becoming increasingly crucial in investment decision-making processes, providing insights into non-financial aspects of Upstream Bio's operations that may have significant financial implications and affect Upstream Bio's stock price as well as guide investors towards more socially responsible investments.

Upstream Market Capitalization

The company currently falls under 'Mid-Cap' category with a total capitalization of 1.26 B.

Upstream Profitablity

Last ReportedProjected for Next Year
Return On Tangible Assets(0.13)(0.12)
Return On Capital Employed(0.15)(0.16)
Return On Assets(0.13)(0.12)
Return On Equity(0.13)(0.15)

Management Efficiency

Upstream Bio has Return on Asset of (0.2815) % which means that on every $100 spent on assets, it lost $0.2815. This is way below average. In the same way, it shows a return on shareholders' equity (ROE) of (0.408) %, meaning that it generated no profit with money invested by stockholders. Upstream Bio's management efficiency ratios could be used to measure how well Upstream Bio manages its routine affairs as well as how well it operates its assets and liabilities. The current year's Return On Tangible Assets is expected to grow to -0.12. In addition to that, Return On Capital Employed is expected to decline to -0.16. At present, Upstream Bio's Total Assets are projected to increase significantly based on the last few years of reporting. The current year's Non Current Assets Total is expected to grow to about 3.1 M, whereas Other Current Assets are forecasted to decline to about 5.6 M.
Last ReportedProjected for Next Year
Book Value Per Share 8.24  8.65 
Tangible Book Value Per Share 8.24  8.65 
Enterprise Value Over EBITDA(6.03)(6.33)
Price Book Value Ratio 1.62  1.70 
Enterprise Value Multiple(6.03)(6.33)
Price Fair Value 1.62  1.70 
Enterprise Value468 M416 M
Effective leadership at Upstream Bio drives its competitive edge in the market. Our analysis focuses on how this translates to financial performance and stock value.
Operating Margin
(55.39)
Return On Assets
(0.28)
Return On Equity
(0.41)

Technical Drivers

As of the 2nd of January, Upstream Bio has the Risk Adjusted Performance of 0.1353, coefficient of variation of 555.51, and Semi Deviation of 3.27. In relation to fundamental indicators, the technical analysis model makes it possible for you to check existing technical drivers of Upstream Bio, as well as the relationship between them.

Upstream Bio Price Movement Analysis

Incorrect Input. Please change your parameters or increase the time horizon required for running this function. The output start index for this execution was zero with a total number of output elements of zero. The Triple Exponential Moving Average (T3) indicator is developed by Tim Tillson as Upstream Bio price series composite of a single exponential moving average, a double exponential moving average and a triple exponential moving average.

Upstream Bio Insider Trading Activities

Some recent studies suggest that insider trading raises the cost of capital for securities issuers and decreases overall economic growth. Trading by specific Upstream Bio insiders, such as employees or executives, is commonly permitted as long as it does not rely on Upstream Bio's material information that is not in the public domain. Local jurisdictions usually require such trading to be reported in order to monitor insider transactions. In many U.S. states, trading conducted by corporate officers, key employees, directors, or significant shareholders must be reported to the regulator or publicly disclosed, usually within a few business days of the trade. In these cases Upstream Bio insiders are required to file a Form 4 with the U.S. Securities and Exchange Commission (SEC) when buying or selling shares of their own companies.

Upstream Bio Outstanding Bonds

Upstream Bio issues bonds to finance its operations. Corporate bonds make up one of the largest components of the U.S. bond market, which is considered the world's largest securities market. Upstream Bio uses the proceeds from bond sales for a wide variety of purposes, including financing ongoing mergers and acquisitions, buying new equipment, investing in research and development, buying back their own stock, paying dividends to shareholders, and even refinancing existing debt. Most Upstream bonds can be classified according to their maturity, which is the date when Upstream Bio has to pay back the principal to investors. Maturities can be short-term, medium-term, or long-term (more than ten years). Longer-term bonds usually offer higher interest rates but may entail additional risks.

Upstream Bio Predictive Daily Indicators

Upstream Bio intraday indicators are useful technical analysis tools used by many experienced traders. Just like the conventional technical analysis, daily indicators help intraday investors to analyze the price movement with the timing of Upstream Bio stock daily movement. By combining multiple daily indicators into a single trading strategy, you can limit your risk while still earning strong returns on your managed positions.

Upstream Bio Corporate Filings

13A
14th of November 2025
An amended filing to the original Schedule 13G
ViewVerify
8K
5th of November 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
13A
24th of October 2025
The form used by investors holding more than 5% of a company's stock, to report their beneficial ownership pursuant to Rule 13d-1 or Rule 13d-2 under the Securities Exchange Act of 1934
ViewVerify
8K
2nd of September 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
8K
6th of August 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
F4
12th of June 2025
The report filed by a party regarding the acquisition or disposition of a company's common stock, as well as derivative securities such as options, warrants, and convertible securities
ViewVerify
8K
6th of May 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
17th of April 2025
Other Reports
ViewVerify

Upstream Bio Forecast Models

Upstream Bio's time-series forecasting models are one of many Upstream Bio's stock analysis techniques aimed at predicting future share value based on previously observed values. Time-series forecasting models ae widely used for non-stationary data. Non-stationary data are called the data whose statistical properties e.g. the mean and standard deviation are not constant over time but instead, these metrics vary over time. These non-stationary Upstream Bio's historical data is usually called time-series. Some empirical experimentation suggests that the statistical forecasting models outperform the models based exclusively on fundamental analysis to predict the direction of the market movement and maximize returns from investment trading.

Upstream Bio Bond Ratings

Upstream Bio financial ratings play a critical role in determining how much Upstream Bio have to pay to access credit markets, i.e., the amount of interest on their issued debt. The threshold between investment-grade and speculative-grade ratings has important market implications for Upstream Bio's borrowing costs.
Piotroski F Score
5
HealthyView
Beneish M Score
(3.50)
Unlikely ManipulatorView

Upstream Bio Total Assets Over Time

Upstream Bio Assets Financed by Debt

The debt-to-assets ratio shows the degree to which Upstream Bio uses debt to finance its assets. It includes both long-term and short-term borrowings maturing within one year. It also includes both tangible and intangible assets, such as goodwill.

Upstream Bio Debt Ratio

    
  0.34   
It appears most of the Upstream Bio's assets are financed through equity. Typically, companies with high debt-to-asset ratios are said to be highly leveraged. The higher the ratio, the greater risk will be associated with the Upstream Bio's operation. In addition, a high debt-to-assets ratio may indicate a low borrowing capacity of Upstream Bio, which in turn will lower the firm's financial flexibility.

Upstream Bio Corporate Bonds Issued

Most Upstream bonds can be classified according to their maturity, which is the date when Upstream Bio has to pay back the principal to investors. Maturities can be short-term, medium-term, or long-term (more than ten years). Longer-term bonds usually offer higher interest rates but may entail additional risks.

Upstream Short Long Term Debt Total

Short Long Term Debt Total

2.21 Million

At present, Upstream Bio's Short and Long Term Debt Total is projected to increase significantly based on the last few years of reporting.

About Upstream Stock Analysis

Stock analysis is the technique used by a trader or investor to examine and evaluate how Upstream Bio prices is reacting to, or reflecting on a current market direction and economic conditions. It can be used to make informed decisions about market timing, and when buying or selling Upstream shares will generate the highest return on investment. We also built our stock analysis module to help investors to gain an insight into the world economy as a whole, the stock market, thematic ideas. a specific sector, or an individual Stock such as Upstream Bio. By using and applying Upstream Stock analysis, traders can create a robust methodology for identifying Upstream entry and exit points for their positions.
Last ReportedProjected for Next Year
Pretax Profit Margin(30.48)(32.00)
Operating Profit Margin(37.73)(39.62)
Net Loss(30.48)(32.00)

Current Upstream Analysis - Recommendations

We track the performance of the top 100 financial experts across various large and mid-size financial boutiques. Upstream analyst recommendations are determined by taking all analyst recommendations and averaging them as Strong Buy, Buy, Hold, Strong Sell or Sell. There is no one specific way to measure analysis performance other than comparing it to the past results via a very sophisticated attribution analysis. Upstream analyst consensus and target price projections should be used in combination with other traditional techniques such as stock price forecasting, technical analysis, earnings estimate, and various momentum models.
Target PriceAdvice# of Analysts
49.75Strong Buy4Odds
Upstream Bio current and past analyst recommendations published by a number of research institutions as well as average analyst consensus.
Most Upstream analysts issue ratings four times a year, at intervals of three months. Ratings are usually accompanied by a target price to helps potential investors understand Upstream stock's fair price compared to its market value. Analysts arrive at stock ratings after researching public financial statements of Upstream Bio, talking to its executives and customers, or listening to Upstream conference calls.
Upstream Analyst Advice Details

Upstream Stock Analysis Indicators

Upstream Bio stock analysis indicators help investors evaluate how Upstream Bio stock reacts to ongoing and evolving market conditions. The investors can use it to make informed decisions about market timing and determine when trading Upstream Bio shares will generate the highest return on investment. By understating and applying Upstream Bio stock analysis, traders can identify Upstream Bio position entry and exit signals to maximize returns.
Begin Period Cash Flow25.8 M
Common Stock Shares Outstanding51.3 M
Total Stockholder Equity469.9 M
Total Cashflows From Investing Activities-59.5 M
Property Plant And Equipment Net2.4 M
Cash And Short Term Investments470.5 M
Cash325.9 M
Accounts PayableM
Net Debt-324.1 M
50 Day M A20.3268
Total Current Liabilities10.7 M
Other Operating Expenses80.1 M
Non Current Assets Total2.6 M
Non Currrent Assets Other194 K
Stock Based CompensationM

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