Denali Therapeutics Stock Performance

DNLI Stock  USD 22.53  1.06  4.49%   
The firm shows a Beta (market volatility) of 1.58, which means a somewhat significant risk relative to the market. As the market goes up, the company is expected to outperform it. However, if the market returns are negative, Denali Therapeutics will likely underperform. At this point, Denali Therapeutics has a negative expected return of -0.48%. Please make sure to confirm Denali Therapeutics' maximum drawdown, as well as the relationship between the accumulation distribution and day typical price , to decide if Denali Therapeutics performance from the past will be repeated at some point in the near future.

Risk-Adjusted Performance

Very Weak

 
Weak
 
Strong
Over the last 90 days Denali Therapeutics has generated negative risk-adjusted returns adding no value to investors with long positions. Despite weak performance in the last few months, the Stock's essential indicators remain fairly strong which may send shares a bit higher in March 2025. The recent confusion may also be a sign of long-lasting up-swing for the firm traders. ...more

Actual Historical Performance (%)

One Day Return
(4.49)
Five Day Return
(3.59)
Year To Date Return
8.11
Ten Year Return
5.03
All Time Return
5.03
1
Disposition of 1020 shares by Sato Vicki L of Denali Therapeutics at 30.0 subject to Rule 16b-3
11/07/2024
2
Denali Q3 Earnings Miss Estimates, Pipeline Progress Encouraging
11/08/2024
3
Acquisition by Sato Vicki L of 17901 shares of Denali Therapeutics at 18.56 subject to Rule 16b-3
11/19/2024
4
Disposition of 20516 shares by Schuth Alexander O. of Denali Therapeutics at 0.68 subject to Rule 16b-3
11/22/2024
5
Disposition of 17845 shares by Ho Carole of Denali Therapeutics at 0.68 subject to Rule 16b-3
11/25/2024
6
Denali Starts Dosing in Phase II Parkinsons Disease Study
12/06/2024
7
Disposition of 6708 shares by Schuth Alexander O. of Denali Therapeutics at 5.28 subject to Rule 16b-3
12/27/2024
8
Disposition of 30000 shares by Steve Krognes of Denali Therapeutics at 20.25 subject to Rule 16b-3
12/31/2024
9
Disposition of 3080 shares by Sato Vicki L of Denali Therapeutics at 20.91 subject to Rule 16b-3
01/02/2025
10
Acquisition by Ho Carole of 162540 shares of Denali Therapeutics at 21.26 subject to Rule 16b-3
01/03/2025
11
Denali Therapeutics Inc Announces Topline Results from HEALEY ALS Platform Trial
01/06/2025
12
Denali Therapeutics Announces U.S. FDA Breakthrough Therapy Designation Granted to Tividenofusp ...
01/08/2025
13
Denali Therapeutics Announces Key Anticipated 2025 Milestones and Priorities to Further Advance ...
01/13/2025
14
Why Is Denali Therapeutics Stock Trading Higher On Wednesday
01/15/2025
15
Acquisition by Klein Peter S of 17901 shares of Denali Therapeutics at 18.56 subject to Rule 16b-3
01/22/2025
16
Acquisition by Ryan Watts of 162540 shares of Denali Therapeutics at 21.26 subject to Rule 16b-3
01/24/2025
17
Amgen Set to Report Q4 Earnings Is a Beat in the Cards
01/29/2025
18
What is Zacks Researchs Estimate for DNLI FY2024 Earnings
01/31/2025
19
Denali Therapeutics Inc Announces Promising Long-Term Data for Hunter Syndrome Treatment
02/06/2025
Begin Period Cash Flow219.5 M
  

Denali Therapeutics Relative Risk vs. Return Landscape

If you would invest  3,158  in Denali Therapeutics on November 9, 2024 and sell it today you would lose (905.00) from holding Denali Therapeutics or give up 28.66% of portfolio value over 90 days. Denali Therapeutics is currently does not generate positive expected returns and assumes 4.1912% risk (volatility on return distribution) over the 90 days horizon. In different words, 37% of stocks are less volatile than Denali, and 99% of all traded equity instruments are projected to make higher returns than the company over the 90 days investment horizon.
  Expected Return   
       Risk  
Given the investment horizon of 90 days Denali Therapeutics is expected to under-perform the market. In addition to that, the company is 5.84 times more volatile than its market benchmark. It trades about -0.12 of its total potential returns per unit of risk. The Dow Jones Industrial is currently generating roughly 0.03 per unit of volatility.

Denali Therapeutics Market Risk Analysis

Today, many novice investors tend to focus exclusively on investment returns with little concern for Denali Therapeutics' investment risk. Standard deviation is the most common way to measure market volatility of stocks, such as Denali Therapeutics, and traders can use it to determine the average amount a Denali Therapeutics' price has deviated from the expected return over a period of time. It is calculated by determining the expected price for the established period and then subtracting this figure from each price point. The differences are then squared, summed, and averaged to produce the variance.

Sharpe Ratio = -0.1155

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Negative ReturnsDNLI

Estimated Market Risk

 4.19
  actual daily
37
63% of assets are more volatile

Expected Return

 -0.48
  actual daily
0
Most of other assets have higher returns

Risk-Adjusted Return

 -0.12
  actual daily
0
Most of other assets perform better
Based on monthly moving average Denali Therapeutics is not performing at its full potential. However, if added to a well diversified portfolio the total return can be enhanced and market risk can be reduced. You can increase risk-adjusted return of Denali Therapeutics by adding Denali Therapeutics to a well-diversified portfolio.

Denali Therapeutics Fundamentals Growth

Denali Stock prices reflect investors' perceptions of the future prospects and financial health of Denali Therapeutics, and Denali Therapeutics fundamentals are critical determinants of its market performance. Overall, investors pay close attention to revenue and earnings growth, profit margins, and debt levels. These fundamentals can have a significant impact on Denali Stock performance.

About Denali Therapeutics Performance

By evaluating Denali Therapeutics' fundamental ratios, stakeholders can gain valuable insights into Denali Therapeutics' financial health, operational efficiency, and overall profitability, helping them make informed investment and management decisions. For instance, if Denali Therapeutics has a high ROA and ROE, it suggests that the company is efficiently using its assets and equity to generate substantial profits, making it an attractive investment. Conversely, if Denali Therapeutics has a low ROA and ROE, it may indicate underlying issues in asset and equity management, signaling a need for operational improvements. Please also refer to our technical analysis and fundamental analysis pages.
Last ReportedProjected for Next Year
Days Of Inventory On Hand(298.46)(313.38)
Return On Tangible Assets(0.11)(0.12)
Return On Capital Employed(0.16)(0.17)
Return On Assets(0.11)(0.12)
Return On Equity(0.16)(0.17)

Things to note about Denali Therapeutics performance evaluation

Checking the ongoing alerts about Denali Therapeutics for important developments is a great way to find new opportunities for your next move. Stock alerts and notifications screener for Denali Therapeutics help investors to be notified of important events, changes in technical or fundamental conditions, and significant headlines that can affect investment decisions.
Denali Therapeutics generated a negative expected return over the last 90 days
Denali Therapeutics has high historical volatility and very poor performance
The company reported the previous year's revenue of 330.53 M. Net Loss for the year was (145.22 M) with loss before overhead, payroll, taxes, and interest of (412.36 M).
Denali Therapeutics currently holds about 1.07 B in cash with (357.99 M) of positive cash flow from operations. This results in cash-per-share (CPS) ratio of 8.66.
Over 91.0% of the company shares are held by institutions such as insurance companies
Latest headline from gurufocus.com: Denali Therapeutics Inc Announces Promising Long-Term Data for Hunter Syndrome Treatment
Evaluating Denali Therapeutics' performance can involve analyzing a variety of financial metrics and factors. Some of the key considerations to evaluate Denali Therapeutics' stock performance include:
  • Analyzing Denali Therapeutics' financial statements, including its income statement, balance sheet, and cash flow statement, helps in understanding its overall financial health and growth potential.
  • Getting a closer look at valuation ratios like price-to-earnings (P/E) ratio, price-to-sales (P/S) ratio, and price-to-book (P/B) ratio help in understanding whether Denali Therapeutics' stock is overvalued or undervalued compared to its peers.
  • Examining Denali Therapeutics' industry or sector and how it is performing can give you an idea of its growth potential and how it is positioned relative to its competitors.
  • Evaluating Denali Therapeutics' management team can have a significant impact on its success or failure. Reviewing the track record and experience of Denali Therapeutics' management team can help you assess the Company's leadership.
  • Pay attention to analyst opinions and ratings of Denali Therapeutics' stock. These opinions can provide insight into Denali Therapeutics' potential for growth and whether the stock is currently undervalued or overvalued.
It's essential to remember that evaluating Denali Therapeutics' stock performance is not an exact science, and many factors can impact Denali Therapeutics' stock market price. Therefore, it's also important to diversify your portfolio and not rely solely on one company or stock for your investments.

Complementary Tools for Denali Stock analysis

When running Denali Therapeutics' price analysis, check to measure Denali Therapeutics' market volatility, profitability, liquidity, solvency, efficiency, growth potential, financial leverage, and other vital indicators. We have many different tools that can be utilized to determine how healthy Denali Therapeutics is operating at the current time. Most of Denali Therapeutics' value examination focuses on studying past and present price action to predict the probability of Denali Therapeutics' future price movements. You can analyze the entity against its peers and the financial market as a whole to determine factors that move Denali Therapeutics' price. Additionally, you may evaluate how the addition of Denali Therapeutics to your portfolios can decrease your overall portfolio volatility.
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